Ọgwụ anụmanụ dị irè nke Colistin Sulfate CAS 1264-72-8

Nkọwa Ngwaahịa

Ọ na-enwe mmetụta dị ike nke nje bacteria na-adịghị mma na gram, nje bacteria ndị na-adịghị emetụta ya gụnyere Pseudomonas aeruginosa, Escherichia coli, Enterobacteria, Klebsiella, Salmonella, Shigella, Pasteurella na Vibrio. Proteus, Brucella, Serratia na nje bacteria Gram-positive niile na-eguzogide ọgwụ a.Colistin Sulfatemaka ọgwụ nje nwayọ nwayọ, ọrụ bụ isi na akpụkpọ ahụ mkpụrụ ndụ nje, mgbe ọ na-akpakọrịta na nje bacteria dị nro, usoro kemịkalụ ya nke amino efu (Yang) na phosphate ester nke mgbọrọgwụ phosphoric acid na akpụkpọ ahụ mkpụrụ ndụ nje (na electronegative), na-eme ka akpụkpọ ahụ dịkwuo mma, na-eme ka mkpụrụ ndụ nke ihe dị mkpa dị ka amino acid, Piao songs, pyrimidine, K + ya dịkwuo elu.

Aitinye akwụkwọ

A na-ejikarị ya agwọ ọrịa eriri afọ nke Grame-negative bacilli (Escherichia coli, wdg) kpatara. Ọ na-arụkwa ọrụ nke ọma megide Pseudomonas aeruginosa (sepsis, ọrịa urinary tract, ọkụ ma ọ bụ ọrịa ọnya na-akpata).

atụmatụ

(1) O nwere oke iguzogide nje bacteria Gram na-adịghị mma. Karịsịa, o nwere mmetụta kpọmkwem na mmepe na Escherichia coli, Salmonella, na Pseudomonas aeruginosa.

(2) Ọ na-egbu nje bacteria. Site n'igbochi ọrụ nke membranes cell permeability, nje bacteria na-anwụ.

(3) Ọ fọrọ nke nta ka ọ bụrụ na enweghị nsogbu ọ bụla na iguzogide ọgwụ. A hụghị ihe ọ bụla na-eguzogide R-factor.

(4) Ọ na-arụ ọrụ nke ọma na ọgwụ nje bacteria na-egbochi Gram positive. Mgbe ejikọtara ya na zinc bacitracin, flavomycin, sulfonamides, penicillin semi synthetic, gentamicin, wdg, mmetụta ya na-aka mma.

(5) Enweghị ihe fọdụrụ. Mgbe e ji ọnụ nye ya, ọ fọrọ nke nta ka ọ ghara ịmịkọrọ eriri afọ ya, mana n'oge a na-agba ya n'ime akwara, a na-anakọta ọbara ma na-amịkọrọ ya nke ọma, yabụ ọ dịghị mkpa ichegbu onwe gị maka ihe fọdụrụ n'ime ihe anụmanụ.

(6) Kwalite uto nke anụ ụlọ na anụ ọkụkọ, ma gbochie ma chịkwaa ọrịa enteritis na-efe efe n'anụ ụlọ na anụ ọkụkọ.