Ọgwụ ọgwụgwọ ọrịa anụmanụ nke ọma Colistin Sulfate CAS 1264-72-8
Nkọwa ngwaahịa
Ọ na-enwekarị mmetụta antibacterial siri ike na nje bacteria gram-adịghị mma, nje bacteria na-enwe mmetụta gụnyere Pseudomonas aeruginosa, Escherichia coli, Enterobacteria, Klebsiella, Salmonella, Shigella, Pasteurella na Vibrio.Proteus, Brucella, Serratia na nje bacteria niile nwere gram na-eguzogide ọgwụ a.Colistin sulfatemaka ngwa ngwa disinfectant, ọrụ bụ isi na akpụkpọ ahụ sel nje, mgbe kọntaktị na nje bacteria nwere mmetụta, usoro kemịkalụ ya nke amino (Yang) na phosphate ester nke mgbọrọgwụ phosphoric acid na akpụkpọ ahụ nke nje bacteria (ya na electronegative), na-abawanye permeability nke akpụkpọ ahụ. , na-eme ka cell nke ihe ndị dị mkpa dị ka amino acids, egwu Piao, pyrimidine, K + ya.
Angwa
A na-ejikarị agwọ ọrịa eriri afọ nke Grame-negative bacilli (Escherichia coli, wdg) kpatara.Ọ dịkwa irè megide Pseudomonas aeruginosa (sepsis, ọrịa urinary tract, ọkụ ma ọ bụ ọrịa ọnya ọnya).
Atụmatụ
(1) Ọ nwere oke ike iguzogide nje bacteria Gram negative.Karịsịa, ọ nwere mmetụta mgbochi mmepe kpọmkwem na Escherichia coli, Salmonella, na Pseudomonas aeruginosa.
(2) Ọ nwere mmetụta bactericidal.Site na igbochi ọrụ permeability nhọrọ nke membranes cell, nje bacteria na-anwụ.
(3) Ọ fọrọ nke nta ka ọ bụrụ na ọ nweghị nsogbu ọ bụla na nguzogide ọgwụ.Enweghị ihe mgbochi R-factor ahụghị.
(4) Ọ na-arụ ọrụ synergistically na anti gram positive bacteria ọgwụ.Mgbe ejikọtara ya na zinc bacitracin, flavomycin, sulfonamides, penicillin semi synthetic, gentamicin, wdg, mmetụta ahụ ka mma.
(5) Enweghị ihe fọdụrụ.Mgbe a na-enye ya ọnụ, ọ fọrọ nke nta ka ọ ghara itinye ya n'ime eriri afọ, ma n'oge injection intramuscular, nchịkọta ọbara na absorption dị mma, n'ihi ya, ọ dịghị mkpa ichegbu onwe gị banyere ihe fọdụrụ na ngwaahịa anụmanụ.
(6) Kwalite uto nke anụ ụlọ na anụ ọkụkọ, ma gbochie ma chịkwaa enteritis na-efe efe na anụ ụlọ na anụ ọkụkọ.